DrugDigest  
 
    Search
 
  Drugs & Herbs
  Conditions
  News & Reviews
7 Steps to Safety
Check For Savings
Senior Corner
Glossary
eBulletins
Home
Express Scripts Member?

Herbs & Supplements

Aloe species
Scientific Name: Aloe
Other Names: Aloe barbadensis, Aloe vera, Burn Plant, Cape Aloe

References

67 Fed. Reg. 31,125-31,127 (May 9, 2002). Status of Certain Additional Over-the-Counter Drug Category II and III Active Ingredients. Final Rule.

Agarwal OP. Prevention of atheromatous heart disease. Angiology. 1985;36(8):485-492.

Ajabnoor MA. Effect of aloes on blood glucose levels in normal and alloxan diabetic mice. Journal of Ethnopharmacology. 1990;28(2):215-220.

Akev N, Turkay G, Can A, et al. Effect of Aloe vera leaf pulp extract on Ehrlich ascites tumours [sic] in mice. European Journal of Cancer Prevention. 2007;16(2):151-157.

Allen J. OTC laxatives that contain aloe or cascara will either go off the market or be reformulated. Pharmacist's Letter/Prescriber's Letter 2002;18:180614.

Arosio B, Gagliano N, Fusaro LM, et al. Aloe-Emodin quinone pretreatment reduces acute liver injury induced by carbon tetrachloride. Pharmacology and Toxicology. 2000;87(5):229-233.

Banvard E. Aloe vera (aloe barbadensis). Earlham College. April 4, 2003. Available at: http://www.earlham.edu/~banvael/aloevera.html. Accessed April 14, 2004.

Beppu H, Koike T, Shimpo K, et al. Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats. Journal of Ethnopharmacology. 2003;89(1):37-45.

Bergamante V, Ceschel GC, Marazzita S, Ronchi C, Fini A. Effect of vehicles on topical application of aloe vera and arnica montana components. Drug Delivery. 2007;14(7):427-432.

Beppu H, Shimpo K, Chihara T, et al. Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components. Journal of Ethnopharmacology. 2006;103(3):468-477.

Blitz JJ, Smith JW, Gerard JR. Aloe vera gel in peptic ulcer therapy: preliminary report. Journal of the American Osteopathic Association. 1963;62:731-735.

Blumenthal M, Gruenwald J, Hall T, Rister RS, eds. The Complete German Commission E Monographs. Austin, Texas: American Botanical Council; 1998.

Bolkent S, Akev N, Ozsoy N, Sengezer-Inceli M, Can A, Alper O, Yanardag R. Effect of Aloe vera (L.) Burm. fil. leaf gel and pulp extracts on kidney in type-II diabetic rat models. Indian Journal of Experimental Biology. 2004;42(1):48-52.

Borrelli F, Izzo AA. The plant kingdom as a source of anti-ulcer remedies. Phytotherapy Research. 2000;14(8):581-191.

Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Annals of Pharmacotherapy. 2007;41(10):1740-1743.

Brusick D, Mengs U. Assessment of the genotoxic risk from laxative senna products. Environmental and Molecular Mutagens. 1997;29(1):1-9.

Buenz EJ. Aloin induces apoptosis in Jurkat cells. Toxicology In Vitro. 2008;22(2):422-429.

Bunyapraphatsara N, Chansrakaew W, Pornchirasilp S, Peungvicha P, Chokechaijaroenporn O. Antidiabetic effect of fresh and preserved aloe gel. Thailand Journal of Phytopharmacy. 195;2(2):9-15.

Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, et al. Antidiabetic activity of Aloe vera juice. II Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine 1996; 3,3:245-248.

Can A, Akev N, Ozsoy N, et al. Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models. Biological and Pharmaceutical Bulletin. 2004;27(5):694-698.

Cardenas C, Quesada AR, Medina MA. Evaluation of the anti-angiogenic effect of aloe-emodin. Cellular and Molecular Life Sciences. 2006;63(24):3083-3089.

Chandan BK, Saxena AK, Shukla S, et al. Hepatoprotective potential of Aloe barbadensis Mill. against carbon tetrachloride induced hepatotoxicity. Journal of Ethnopharmacology. Epublished ahead of print. January 24, 2007.

Chaudhary G, Saini MR, Goyal PK. Chemopreventive potential of Aloe vera against 7,12-dimethylbenz(a)anthracene induced skin papillomagenesis in mice. Integrated Cancer Therapy. 2007;6(4):405-412.

Chen SH, Lin KY, Chang CC, Fang CL, Lin CP. Aloe-emodin-induced apoptosis in human gastric carcinoma cells. Food Chemistry and Toxicology. 2007;45(11):2296-2303.

Choonhakarn C, Busaracome P, Sripanidkulchai B, Sarakarn P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. British Journal of Dermatology. 2008;158(3):573-577.

Cole L, Heard C. Skin permeation enhancement potential of Aloe Vera and a proposed mechanism of action based upon size exclusion and pull effect. International Journal of Pharmaceutics. 2007;333(1-2):10-16.

Dal'Belo SE, Gaspar LR, Maia Campos PM. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Research Technology. 2006;12(4):241-246.

Davis RH, Donato JJ, Hartman GM, Haas RC. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Journal of the American Podiatric Medical Association. 1994;84(2):77-81.

Davis RH, Leitner MG, Russo JM, Byrne ME. Anti-inflammatory activity of Aloe vera against a spectrum of irritants. Journal of the American Podiatric Medical Association. 1989;79(6):263-276.

Davis RH, Rosenthal KY, Cesario LR, Rouw GA. Processed Aloe vera administered topically inhibits inflammation. Journal of the American Podiatric Medical Association. 1989;79(8):395-397.

Duansak D, Somboonwong J, Patumraj S. Effects of Aloe vera on leukocyte adhesion and TNF-alpha and IL-6 levels in burn wounded rats. Clinical Hemorheology and Microcirculation. 2003;29(3-4):239-246.

Dutta A, Bandyopadhyay S, Mandal C, Chatterjee M. Aloe vera leaf exudate induces a caspase-independent cell death in Leishmania donovani promastigotes. Journal of Medical Microbiology. 2007;56(Pt 5):629-636.

Dutta A, Mandal G, Mandal C, Chatterjee M. In vitro antileishmanial activity of Aloe vera leaf exudate: A potential herbal therapy in leishmaniasis. Glycoconjugate Journal. 2007;24(1):81-86.

Dutta A, Sarkar D, Gurib-Fakim A, Mandal C, Chatterjee M. In vitro and in vivo activity of Aloe vera leaf exudate in experimental visceral leishmaniasis. Parasitology Research. Epublished ahead of print. February 12, 2008.

Eamlamnam K, Patumraj S, Visedopas N, Thong-Ngam D. Effects of Aloe vera and sucralfate on gastric microcirculatory changes, cytokine levels and gastric ulcer healing in rats. World Journal of Gastroenterology. 2006;12(13):2034-2039.

Ernst E, Pittler MH, Stevinson C. Complementary/alternative medicine in dermatology: evidence-assessed efficacy of two diseases and two treatments. American Journal of Clinical Dermatology. 2002;3(5):341-348.

Ernst E. Adverse effects of herbal drugs in dermatology. British Journal of Dermatology. 2000;143(5):923-929.

Esua MF, Rauwald JW. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays. Carbohydrate Research. 2006;341(3):355-364.

Etim OE, Farombi EO, Usoh IF, Akpan EJ. The protective effect of aloe vera juice on lindane induced hepatotoxicity and genotoxicity. Pakistani Journal of Pharmaceutical Sciences. 2006;19(4):337-340.

Evangelos C, Spyros K, Spyros D. Henoch-Schonlein purpura associated with Aloe vera administration. European Journal of Internal Medicine. 2005;16(1):59-60.

Food and Drug Administration, HHS. Status of certain additional over-the counter drug category II and III active ingredients. Final rule. Federal Register. 2002;67:31125-31127.

Ford JL, Phillips P. Are aloe-coated gloves effective in healthcare? Nursing Times. 2007;103(10):40-41.

Geremias R, Pedrosa RC, Locatelli C, de Favere VT, Coury-Pedrosa R, Laranjeira MC. Lipid lowering activity of hydrosoluble chitosan and association with Aloe vera L. and Brassica olearaceae L. Phytotherapy Research. 2006;20(4):288-293.

Ghannam N, Kingston M, Al-Meshaal IA, Tariq M, Parman NS, Woodhouse N. The antidiabetic activity of aloes: preliminary clinical and experimental observations. Hormone Research. 1986;24(4):288-294.

Gilman EF. Aloe barbadensis. University of Florida Fact Sheet FPS-34. October 1999. Available at: http://www.hort.ufl.edu/shrubs/ALOBARA.PDF. Accessed April 14, 2004.

Graf J. Herbal anti-inflammatory agents for skin disease. Skin Therapy Letter. 2000;5(4):3-5.

Grieve M. Aloes. In: A Modern Herbal. New York: Dover Publishers, 1971. Available at: http://www.botanical.com/botanical/mgmh/mgmh.html Posted 1995. Accessed April 14, 2004.

Grindlay D, Reynolds T. The Aloe vera phenomenon: a review of the properties and modern uses of the leaf parenchyma gel. Journal of Ethnopharmacology. 1986;16(2-3):117-151.

Guo J, Xiao B, Zhang S, Liu D, Liao Y, Sun Q. Growth Inhibitory Effects of Gastric Cancer Cells with an Increase in S Phase and Alkaline Phosphatase Activity Repression by Aloe-Emodin. Cancer Biology and Therapy. 2007;6(1):85-88.

Gupta R, Flora SJ. Protective value of Aloe vera against some toxic effects of arsenic in rats. Phytotherapy Research. 2005;19(1):23-28.

Heggers JP, Robson MC, Manavalen K, et al. Experimental and clinical observations on frostbite. Annals of Emergency Medicine. 1987;16(9):1056-1062.

Herbs2000. Aloe vera syn. A. barbadensis. No date given. Available at: http://www.herbs2000.com/herbs/herbs_aloe_vera.htm. Accessed April 20, 2004.

Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine. 1994;1:161-171.

Hu Y, Xu J, Hu Q. Evaluation of antioxidant potential of aloe vera (Aloe barbadensis miller) extracts. Journal of Agricultural and Food Chemistry. 2003;51(26):7788-7791.

Hunter D, Frumkin A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis. 1991;47(3):193-196.

Hutter JA, Salman M, Stavinoha WB, et al. Antiinflammatory C-glucosyl chromone from Aloe barbadensis. Journal of Natural Products. 1996;59:541-543.

Ikeno Y, Hubbard GB, Lee S, Yu BP, Herlihy JT. The influence of long-term Aloe vera ingestion on age-related disease in male Fischer 344 rats. Phytotherapy Research. 2002;16(8):712-718.

Ishii Y, Takino Y, Toyo'oka T, Tanizawa H. Studies of aloe. VI. Cathartic effect of isobarbaloin. Biological and Pharmaceutical Bulletin. 1998;21(11):1226-1227.

Ishii Y, Tanizawa H, Ikemoto C, Takino Y. Studies of Aloe. I. Cathartic effects [Article in Japanese] Yakugaku Zasshi. 1981;101(3):254-258.

Ishii Y, Tanizawa H, Takino Y. Studies of aloe. II. Mechanism of cathartic effect. [Article in Japanese] Yakugaku Zasshi. 1988;108(9):904-910.

Ishii Y, Tanizawa H, Takino Y. Studies of aloe. III. Mechanism of cathartic effect. Chemical and Pharmaceutical Bulletin (Tokyo). 1990;38(1):197-200.

Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. Biological and Pharmaceutical Bulletin. 1994;17(4):495-497.

Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. Biological and Pharmaceutical Bulletin. 1994;17(5):651-653.

Kar A, Panda S, Bharti S. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Journal of Ethnopharmacology. 2002;81(2):281-285.

Kemper KJ, Chiou V. Aloe vera. The Longwood Herbal Task Force. Revised July 29, 1999. Available at: http://www.longwoodherbal.org/aloe/aloe.htm. Accessed: May 1, 2008.

Klein AD, Penneys NS. Aloe vera. Journal of the American Academy of Dermatology. 1988;18(4 Pt 1):714-720.

Lans CA. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus. Journal of Ethnobiology and Ethnomedicine. 2006;2:45.

Lim BO, Seong NS, Choue RW, et al. Efficacy of dietary aloe vera supplementation on hepatic cholesterol and oxidative status in aged rats. Journal of Nutritional Science and Vitaminology (Tokyo). 2003;49(4):292-296.

Liu C, Leung MY, Koon JC, et al. Macrophage activation by polysaccharide biological response modifier isolated from Aloe vera L. var. chinensis (Haw.) Berg. International Immunopharmacology. 2006;6(11):1634-1641.

Lulinski B, Kapica C. Some notes on aloe vera. Quackwatch. Posted June 23, 1998. Available at: http://www.quackwatch.org/01QuackeryRelatedTopics/DSH/aloe.html. Accessed May 10, 2004.

Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. American Journal of Kidney Diseases. 2002;39(3):E13.

Maenthaisong R, Chaiyakunapruk N, Niruntraporn S, Kongkaew C. The efficacy of aloe vera used for burn wound healing: a systematic review. Burns. 2007;33(6):713-718.

MacKay D, Miller AL. Nutritional support for wound healing. Alternative Medicine Review. 2003;8(4):359-377.

Mantle D, Gok MA, Lennard TW. Adverse and beneficial effects of plant extracts on skin and skin disorders. Adverse Drug Reactions and Toxicology Review. 2001;20(2):89-103.

Matsuda Y, Yokohira M, Suzuki S, et al. One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study. Food Chemistry and Toxicology. 2008;46(2):733-739.

McCauley RL, Heggers JP, Robson MC. Frostbite. Methods to minimize tissue loss. Postgraduate Medicine. 1990;88(8):67-68 and 73-77.

McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997.

Merchant TE, Bosley C, Smith J, et al. A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients. Radiation Oncology. 2007;2:45.

Miller MB, Koltai PJ. Treatment of experimental frostbite with pentoxifylline and aloe vera cream. Archives of Otolaryngology and Head and Neck Surgery. 1995;121(6):678-680.

Moon EJ, Lee YM, Lee OH, et al. A novel angiogenic factor derived from Aloe vera gel: beta-sitosterol, a plant sterol. Angiogenesis. 1999;3(2):117-123.

Morrow DM, Rapaport MJ, Strick RA. Hypersensitivity to aloe. Archives of Dermatology. 1980;116(9):1064-1065.

Muller MJ, Hollyoak MA, Moaveni Z, Brown TL, Herndon DN, Heggers JP. Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin. Burns. 2003;29(8):834-836.

Natural Medicines Comprehensive Database, Online Edition. Pharmacist's Letter/Prescriber's Letter. Stockton CA: Therapeutic Research Facility, 2006. Available at: http://www.pharmacistsletter.com/(S(ulqz3s45omt3ag55um4kj345))/home.aspx?li=1&st=1&cs=&s=ND.

Okyar A, Can A, Akev N, Baktir G, Sutlupinar N. Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models. Phytotherapy Research. 2001;15(2):157-161.

Paulsen E, Korsholm L, Brandrup F. double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. Journal of the European Academy of Dermatology and Venereology. 2005;19(3):326-331.

Pigatto PD, Guzzi G. Aloe linked to thyroid dysfunction [letter]. Archives of Medical Research. 2005;36(5):608.

Plants for a Future Database. Aloe vera. No date given. Available at: http://www.ibiblio.org/pfaf/cgi-bin/arr_html?Aloe+vera. Accessed April 14, 2004.

Pogribna M, Freeman JP, Paine D, Boudreau MD. Effect of Aloe vera whole leaf extract on short chain fatty acids production by Bacteroides fragilis, Bifidobacterium infantis and Eubacterium limosum. Letters in Applied Microbiology. Epublished ahead of print. March 18, 2008.

Rabe C, Musch A, Schirmacher P, Kruis W, Hoffmann R. Acute hepatitis induced by an Aloe vera preparation: a case report. World Journal of Gastroenterology. 2005;11(2):303-204.

Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S. Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clinical and Experimental Pharmacology and Physiology. 2006;33(3):232-237.

Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. Journal of Medicinal Food. 2004;7(1):61-66.

Rajasekaran S, Sivagnanam K, Subramanian S. Mineral contents of aloe vera leaf gel and their role on streptozotocin-induced diabetic rats. Biological Trace Element Research;108(1-3):185-195. Reuter J, Jocher A, Stump J, Grossjohann B, Franke G, Schempp CM. Investigation of the anti-inflammatory potential of Aloe vera gel (97.5%) in the ultraviolet erythema test. Skin Pharmacology and Physiology. 2008;21(2):106-110.

Reynolds T, Dweck AC. Aloe vera leaf gel: a review update. Journal of Ethnopharmacology. 1999;68(1-3):3-37.

Richardson J, Smith JE, McIntyre M, Thomas R, Pilkington K. Aloe vera for preventing radiation-induced skin reactions: a systematic literature review. Clinical Oncology (Royal College of Radiology). 2005;17(6):478-484.

Rodriguez-Fragoso L, Reyes-Esparza J, Burchiel SW, Herrera-Ruiz D, Torres E. Risks and benefits of commonly used herbal medicines in Mexico. Toxicology and Applied Pharmacology. 2008;227(1):125-135.

Roman-Ramos R, Flores-Saenz JL, Partida-Hernandez G, Lara-Lemus A, Alarcon-Aguilar F. Experimental study of the hypoglycemic effect of some antidiabetic plants. Archives of Investigative Medicine (Mexico). 1991;22(1):87-93.

Rosca-Casian O, Parvu M, Vlase L, Tamas M. Antifungal activity of Aloe vera leaves. Fitoterapia. Epublished ahead of print. February 6, 2007.

Saada HN, Ussama ZS, Mahdy AM. Effectiveness of Aloe vera on the antioxidant status of different tissues in irradiated rats. Pharmazie. 2003;58(12):929-931.

Schmidt JM, Greenspoon JS. Aloe vera dermal wound gel is associated with a delay in wound healing. Obstetrics and Gynecology. 1991;78(1):115-117.

Shimpo K, Beppu H, Chihara T, Kaneko T, Shinzato M, Sonoda S. Effects of aloe arborescens ingestion on azoxymethane-induced intestinal carcinogenesis and hematological and biochemical parameters of male F344 rats. Asian Pacific Journal of Cancer Prevention. 2006;7(4):585-590.

Shoji A. Contact dermatitis to Aloe arborescens. Contact Dermatitis. 1982;8(3):164-167.

Siegers CP, von Hertzberg-Lottin E, Otte M, Schneider B. Anthranoid laxative abuse--a risk for colorectal cancer? Gut. 1993;34(8):1099-1101.

Somboonwong J, Thanamittramanee S, Jariyapongskul A, Patumraj S. Therapeutic effects of Aloe vera on cutaneous microcirculation and wound healing in second degree burn model in rats. Journal of the Medical Association of Thailand. 2000;83(4):417-425.

Suvitayavat W, Sumrongkit C, Thirawarapan SS, Bunyapraphatsara N. Effects of Aloe preparation on the histamine-induced gastric secretion in rats. Journal of Ethnopharmacology. 2004;90(2-3):239-247.

Syed TA, Ahmad SA, Holt AH, Ahmad SA, Ahmad SH, Afzal M. Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Tropical Medicine and International Health. 1996;1(4):505-509.

University of Illinois at Chicago, College of Pharmacy. Drug Information Center. Drug Information Update. Why did the FDA ban anthrquinone derivatives in over-the-counter stimulant laxatives? No date given. Available at: http://www.uic.edu/pharmacy/services/di/laxatives.htm. Accessed May 10, 2004.

Vath P, Wamer WG, Falvey DE. Photochemistry and phototoxicity of aloe emodin. Photochemistry and Photobiology. 2002;75(4):346-352.

Vazquez B, Avila G, Segura D, Escalante B. Antiinflammatory activity of extracts from Aloe vera gel. Journal of Ethnopharmacology. 1996;55(1):69-75.

Vinson JA, Al Kharrat H, Andreoli L. Effect of Aloe vera preparations on the human bioavailability of vitamins C and E. Phytomedicine. 2005;12(10):760-765.

Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. British Journal of General Practice. 1999;49(447):823-828.

Wamer WG, Vath P, Falvey DE. In vitro studies on the photobiological properties of aloe emodin and aloin A. Free Radicals in Biology and Medicine. 2003;34(2):233-242.

West DP, Zhu YF. Evaluation of aloe vera gel gloves in the treatment of dry skin associated with occupational exposure. American Journal of Infection Control. 2003;31(1):40-42.

Willems M, van Buuren HR, de Krijger R. Anthranoid self-medication causing rapid development of melanosis coli. Netherlands Journal of Medicine. 2003;61(1):22-24.

Wynn RL. Aloe vera gel: update for dentistry. General Dentistry. 2005;53(1):6-9.

Xiao B, Guo J, Liu D, Zhang S. Aloe-emodin induces in vitro G2/M arrest and alkaline phosphatase activation in human oral cancer KB cells. Oral Oncology. 2007;43(9):905-910.

Yagi A, Kabash A, Mizuno K, Moustafa SM, Khalifa TI, Tsuji H. Radical scavenging glycoprotein inhibiting cyclooxygenase-2 and thromboxane A2 synthase from aloe vera gel. Planta Medica. 2003;69(3):269-271.

Yagi A, Kabash A, Okamura N, Haraguchi H, Moustafa SM, Khalifa TI. Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera. Planta Medica. 2002;68(11):957-960.

Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care. 2003;26(4):1277-1294.

Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera juice. 1. Clinical trial in new cases of diabetes mellitus. Phytomedicine. 1996;3(3):241-243.

Yoo EJ, Lee BM. Chemopreventive effects of aloe against genotoxicity induced by benzo[a]pyrene. Journal of Toxicology and Environmental Health Part A: current issues. 2005;68(21):1841-1860.

Zhang XF, Wang HM, Song YL, et al. Isolation, structure elucidation, antioxidative and immunomodulatory properties of two novel dihydrocoumarins from Aloe vera. Bioorganic and Medicinal Chemistry Letters. 2006;16(4):949-953.

Last Revised May 1, 2008

<< Back


Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.

In general, herbal products are not subject to review or approval by the U.S. Food and Drug Administration (FDA). They are not required to be standardized, meaning that the amounts of active ingredients or contaminants they contain may vary between brands or between different batches of the same brand. Not all of the risks, side effects, or interactions associated with the use of herbal products are known because few reliable studies of their use in humans have been done.

This information is provided for your education only. Please share this information with your healthcare provider and be sure that you talk to your doctor and pharmacist about all the prescription and non-prescription medicines you take before you begin to use any herbal product.

  Learn About

Who is this for?

When should I be careful taking it?

What side effects should I watch for?

What interactions should I watch for?

Should I take it?

> References



Printable Version     Recommend this page to a friend